I generally go with the philosophy of purchase the best you can afford at that point in time - don't skimp on the pc, that little extra you spend now will prolong your PC's life by months and years.
I would think you should focus on:
RAM - as much as possible, 32 gigs will do you well - make sure that your Mobo has 4 slots, if you go for 16, then get 2x8 and you can always add some more later.
CPU - best you can buy, coreI7 (skip the cheap i5's)- see what you can afford.
PSU - this is something I've learnt the hard way, always get a big ass power supply, 700+ Even if the Mobo can run on less it pays to get a larger one in the long run.
HD - Solid state is a bit of a pain due to the size of the drives but if you are intent on getting one, then get a huge drive for your data and then load the OS onto the solid state.
GFX CARD - If you are using software that renders in the GPU then go ahead and get a higher end card, but if you are not then look at a Card with the Max Vram you can get - it will speed up the viewport etc.