I am experiencing the same issue of files unable to load (and unable to merge), except that it happens like once or twice a week. Is anyone else having these issues with 2010? I have been able to use my autobacks and .bak files mostly but it happens on older files too, which makes it scary to even try to open an older file. It doesn't seem to happen when working locally though, so I didn't know if it would have anything to do with our network. Also I am on 32 bit 2010, but we have others working with 64 bit 2010 - could that be an issue too? Anyone have any thoughts?