Yes! That's what makes Vray so great.
I would highly recommend using the vray physical camera to take advantage of exposure settings, the f number and ISO in particular. Uncheck vignetting as not to influence the output. Second, Try to avoid pure 255 white materials as it will create problems, keep it around 249 or so (not scientific) and you should be ok.
the dome, hdri, direct light will all work but before you get carried away try getting the overall lighting as close as possible with just the vray sun and sky or a direct light. The idea is to keep it simple at first. This way you can get a feel for the camera's exposure settings and how it works with the sun's intensity.