There is a huge difference, about 150% to 200% faster, using as reference the FPS stats on a same scene, using Max performance or DirectX. Much more if the scene requires to draw 2D elements (lines, dots...).
Also, with my last card (8800GT) i had many problems using it in Max 2010 / Windows 7: about one second lag selecting objects, jerky movement and so. Instead, this Quadro 4000 with the performance drivers works like a charm.